Driving Discovery, Improving Outcomes – Advancing Appendix Cancer Research for a Better Tomorrow
Progress in appendix cancer starts with bold questions and collaborative science. This page highlights the latest research, emerging treatments, and innovations shaping the future of care. From clinical trials to promising breakthroughs, we spotlight efforts that bring hope to patients and fuel advocacy for change. Whether you’re a patient, caregiver, provider, or researcher—this is where discovery meets determination.
Current Research Projects
Experts publish an action plan to address appendiceal cancer enigmas. They have identified key research priority areas to deliver a fumdamental understanding of appendiceal tumors and to improve treatments and outcomes for patients.
Innovations in Treatment
Breast Cancer Drug Study Shows Promise in Treatment of Appendix Cancer
Summary of Appendicure’s Live Event with Dr. Lowy’s Webinar on 3/26/26
Appendix cancer,once considered an exception now clinicians and researchers now view it with heightened urgency. Improved imaging,genomic profiling,and increased colonoscopy rates have revealed a steady rise in the incidence of appendix cancer
Clinical Trials Directory
Clinical trials play a vital role in advancing treatment options for appendix cancer. This section highlights how to find ongoing studies, emerging therapies, and opportunities to participate in research that may shape future care. Here is an example of a clinical study.
Individualized Response Assessment to Heated Intraperitoneal Chemotherapy (HIPEC) for the Treatment of Peritoneal Carcinomatosis From Ovarian, Colorectal, Appendiceal, or Peritoneal Mesothelioma Histologies
Location:
Bethesda, Maryland, USA
Clinical Trial Link:
https://www.clinicaltrials.gov/study/NCT04847063
Estimated Completion Date:
Dec 30, 2030
Steps to Find a Clinical Trial
Where to Look for Clinical Trials
Keywords for Searching for Clinical Trials
| Appendix Adenocarcinoma | High Grade Appendix Mucinous Neoplasm (HAMN) |
| Appendiceal Cancer | Hyperthermic IntraPeritoneal Chemotherapy (HIPEC) |
| Appendiceal Carcinoma | Low Grade Appendix Mucinous Neoplasm (LAMN) |
| Appendix Cancer | Peritoneal Carcinomatosis |
| Appendix Mucinous Adenocarcinoma | Pressurized IntraPeritoneal Aerosol Chemotherapy (PIPAC) |
Blog Highlights
Why Some Men With Appendix Cancer Still Aren’t Getting CA125 Testing
New research is raising an uncomfortable question. Are some appendix cancer patients, especially men, missing an important tumor marker because of an outdated assumption about who it’s for? For years, appendix cancer patients have had their bloodwork monitored with tumor markers like CEA and CA19-9. CA125, historically associated…
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What Tumor Markers Tell Us Before and After CRS
A new MD Anderson study of 376 cytoreductive surgeries finds that CEA, CA19-9, and CA125, considered together and tracked over time, give surgeons and patients meaningful information about disease burden, surgical outcomes, and the years that follow. FROM OUR COMMUNITYMany Appendicure members have watched their CEA, CA19-9, or…
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What You Need to Know About Stomas in CRS and HIPEC
If you are heading into CRS and HIPEC for appendix cancer, there is a conversation worth having with your surgical team before the day of surgery, and it is the one most patients tell us they wish they had pushed harder for: the stoma conversation. A retrospective study…
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